Advantages over urinalysis
- Simple
- Painless
- No risk of infection
- Cheap
Disadvantages
You should only perform it after a full history and thorough examination!
Indications
- Diabetes Mellitus – polydipsia, polyuria, weight loss, fatigue, infection, DKA
- UTI – dysuria, frequency, back pain, haematuria
- Pregnancy – for monitoring purposes; pre-eclampsia
- Renal and CVD – hypertension, oedema, suspected heart failure
- Drugs – gold, penicillamine, recreational
- Others – anxiety, hysterical polydipsia
Procedure
Mid-stream sample – means that the urine is not-contaminated from any
bacteria on the skin
Men – retract the foreskin, clean the glans penis with a swab. Start to pass urine, and pass the first part into the toilet, then, without stopping the flow, catch some of the middle of the sample in a bottle. Once the bottle is full to the line, then you can continue to pass urine into the toilet
Women – hold back the labia, and clean the vulva with a sterile swab. Start to pass urine, and pass the first part into the toilet, then, without stopping the flow, catch some of the middle of the sample in a bottle. Once the bottle is full to the line, then you can continue to pass urine into the toilet
- Don’t open the bottle until you are ready to take the sample.
- The amount of urine is not that important. Tell patients they don’t have to completely fill the bottle!
- The sample should be tested within 2 hours. If this is not possible, you may be able to preserve the sample to some extent by keeping in the fridge
Testing a Urine Sample
- Wash hands, put on gloves
- Look at the bottle – check it is the right patient and the right date. You also want to know if it was taken in the last 2 hours – a crude way to know if it is recent is to see if it is warm!
- Look in the bottle – are there any precipitations?
- Does it look a normal colour?
- Normal – straw yellow
- Dark – bile pigments may be present due to dehydration
- Red – haematuria, menstrual blood?, food; e.g. beetroot and blackberries
- Green/blue – Pseudomonal UTI, triamterene (this is a potassium sparing diuretic), asparagus
- Orange – dehydration (bile pigments), phenothiazines, carrots
- Clarity – how clear is the sample?
- Cloudy – can be normal (especially in males), may also be bacterial infection (check the smell), WBC, lipids
- Frothy – this suggests proteinurea
- Is there anything in there that shouldn’t be in there?
- Make sure you keep the bottle on the tray, or trolley that it is given to you on! – e.g. in OSCE’s don’t lift it up and put it on the table!
- 4) Open it and have a smell
- Ketones – smell like nail polish remover – diabetes
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