This can be the result of many pathologies and can be acute or chronic.
Common causes
- Atherosclerosis
- Embolism
- Dissection
- External compression by mass lesions
- Fibromuscular dysplasia – non-artherosclerotic, non-inflammatory arterial changes
Common sites of occlusion
- Splanchnic arteries
- Superior mesenteric
- Coeliac arteries – often occurs chronically in women
- Renal arteries
- Bifurcation of the aorta
Signs and symptoms
Acute
- Severe, diffuse abdominal pain
- Rarely involves the liver or spleen
- Renal artery occlusion:
Chronic
- Is often symptomless, unless both the superioer mesenteric and coeliac arteries are occluded, due to large collateral circulation between these two arterial systems
- Intestinal Angina is the most common symptom. This is a cramping pain typically felt 20-60 minutes after eating. Can be relieved by sublingual GTN.
- Patients often lose weight as they develop a fear of eating
- Abdominal bruit may be heard
- Other signs include nausea, vomiting, diarrhoea, constipation and dark stools
- Renal artery occlusion:
Diagnosis
Chronic
- Based mainly on clinical findings
- Angiography may be useful
- In severe cases, bypass surgery can be beneficial, but outcomes vary.
- Angioplasty is also sometimes helpful both with and without stenting
- Some patients may be put on preventative measures and antiplatelet agents
Acute
- Surgical emergency
- Requires thrombolysis or Percutaneous intervention to prevent gut necrosis.
- Outcomes are poor, particularly if >4-6hours after onset
- See more at: http://almostadoctor.co.uk/content/systems/-gastrointestinal-tract/small-intestine/abdominal-artery-ischaemia-and-occlusion#sthash.kKiEXvKZ.dpuf